Lyme disease dating site

Two-tiered testing is necessary because the ELISA may yield false-positive results from antibodies directed against other spirochetes, viral infections or autoimmune diseases.Figure 5) Two-tiered serological testing for Lyme disease.

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These cases may also have a recent past history of EM lesions (single or multiple) and non-specific low-grade fever, myalgia, and fatigue upon questioning further.

Other manifestations (with or without rash) include an isolated facial nerve palsy, arthritis, heart block (or carditis) or meningitis (severe headache, fever), which is usually lymphocytic predominant.

Updated by: Jane Mc Donald, Nicole Le Saux, Infectious Diseases and Immunization Committee Lyme disease, the most common tick-borne infection in Canada and much of the United States, is caused by the bacteria .

Peak incidence for Lyme disease is among children five to nine years of age and older adults (55 to 59 years of age).

Peripheral neuropathy and central nervous system manifestations can also occur, although rarely in children.

Figure 3) Clinical manifestations of confirmed Lyme disease cases (United States, 2001 to 2010).

Early, localized (cutaneous) disease: Erythema migrans (EM) – a rash at the site of a recent tick bite – is the most common presentation in children and adults (Figures 3 and 4).5 cm and mainly flat.

There may be central clearing or some bluish discoloration but a classic bull’s eye is uncommon.

*Sera obtained after antibiotic treatment; percent reactivity refers to the frequency that the different serological assays will be positive depending of the stage of the Lyme disease infection.

EM Erythema migrans; Ig Immunoglobulin; WB Western blot Data adapted from references 4 and 10.

The most common late-stage symptoms are pauciarticular arthritis affecting large joints, especially the knees, which may manifest weeks to months (mean four months) after the tick bite.

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